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孙莉萍

姓名:孙莉萍

职称:教授

电话:0592-2183181

邮箱:sunliping@xmu.edu.cn

个人简历

工作经历:

1998-2000 广州儿童医院住院医师

2000-2003 德累斯顿工业大学医学系遗传实验室

2003-2007 厦门大学医学院任教

2007至今  365游戏官方网站生物材料系任教

2012-2014 以色列魏兹曼科学研究所访问学者

教育经历:

2000-2003 德国德累斯顿工业大学医学系,博士 

1992-1998 同济医科大学,本科


研究领域

纳米生物医学、生物传感器、疾病标志物诊断、天然生物材料


主要科研成果

     

在Advanced Functional Materials、Small、Biosensors and Bioelectronics、Analytical Chemistry等国际权威刊物发表研究论文30余篇,获9项国家发明专利授权。

1. 国家自然科学基金面上项目,81872415,用二维黑磷/纳米金复合材料检测外泌体多重癌症标志物的研究,2019/01-2022/12,主持

2. 国家自然科学基金面上项目,81571764,水凝胶纳米生物传感器用于多重mRNA癌症标记物的联合诊断,2016/01-2019/12,主持

3. 国家自然科学基金面上项目,81171453,纳米金对蛋白质折叠的影响以及对错误折叠蛋白质的识别,2012/01-2015/12,主持

4. 国家自然科学基金青年基金,30900350,用纳米金探针检测卵巢癌线粒体DNA突变的研究,2010/01-2012/12,主持

主要代表学术论著与论文

1. HZ Li, W Xu, F Li, R Zeng, XM Zhang, XW Wang, SJ Zhao, J Weng, Z Li, LP Sun. Amplification of anticancer efficacy by co-delivery of doxorubicin and lonidamine with extracellular vesicles. Drug Delivery. 2022, 29:192-202. 

2. YY Chen,J Peng,T Sheng,RX Qin,SQ Dai,ZF Shi,ZC Tang,LS Wang,QH Zhang,B Han,LP Sun,J Xu,J Weng. Stable radicals with protective umbrellas integrated on the surface of 2D layered materials. Advanced Functional Materials, 2021, 31(42): 2104246.

3. YF Bai, HZ Li, J Xu, YF Huang, XM Zhang, J Weng, Z Li, LP Sun. Ultrasensitive colorimetric biosensor for BRCA1 mutation based on multiple signal amplification strategy. Biosensors and Bioelectronics. 2020. 166:112424.

4. J Gui, YF Bai, HZ Li, J Peng, YF Huang, LP Sun, J Weng. Few-layer black phosphorus as an artificial substrate for DNA replication. ACS Applied Nano Materials. 2020. 3: 1775-1782.

5. X Liu, YF Bai, J Xu, QC Xu, LP Xiao, LP Sun, J Weng, YL Zhao. Robust amphiphobic few-layer black phosphorus nanosheet with improved stability. Advanced Science. 2019. 6:1901991. 

6. YY Chen, J Peng, YQ Lai, BH Wu, LP Sun, J Weng. Ultrasensitive label-free detection of circulating tumor cells using conductivity matching of two-dimensional semiconductor with cancer cell. Biosensors and Bioelectronics. 2019. 142:111520.  

7. LP Sun, Y Zhong, J Gui, XW Wang, XR Zhuang, J Weng. A hydrogel biosensor for high selective and sensitive detection of amyloid-beta oligomers. International Journal of Nanomedicine. 2018. 13: 843-856.

8. J Peng, YQ Lai, YY Chen, J Xu, LP Sun, J Weng. Sensitive detection of carcinoembryonic antigen using stability‐limited few‐layer black phosphorus as an electron donor and a reservoir. Small. 2017. 13: 1603589.

9. Y Zhong, LH Huang, ZS Zhang, YJ Xiong, LP Sun, J Weng. Enhancing the specificity of polymerase chain reaction by graphene through surface modification: zwitterionicpolymeris superior to other polymers with different charges. International journal of nanomedicine. 2016. 11: 5989–6002.

10. J Peng, YJ Xiong, ZQ Lin, LP Sun, J Weng. Few-layer bismuth selenides exfoliated by hemin inhibit amyloid-β1–42 fibrillation. Scientific Reports. 2015.5: 10171.

11. LP Sun, YJ Xiong, A Bashan, E Zimmerman, S Daube, Y Peleg, M Krupkin, D Matzov, M Metz, A Yonath. A recombinant collagen-mRNA platform for controllable protein synthesis. ChemBioChem. 2015.16(10): 1415-1419(封面文章)

12. LP Sun, N Hu, J Peng, LY Chen, J Weng. Ultrasensitive Detection of Mitochondrial DNA Mutation by Graphene Oxide/DNA Hydrogel Electrode.Advanced Functional Materials. 2014. 24(44):6905-6913(封面文章).

13. N Hu, YQ Lai, LP Sun. An efficient electrochemical biosensor for silver ion detection using hydrogen peroxide as a redox indicator. Advanced Materials Research. 2014. 926: 1476-1481.

14. J Peng, J Weng, L Ren, LP Sun. Interactions between gold nanoparticles and amyloid β25-35 peptide. IET Nanobiotechnology. 2014. 8(4): 295-303.

15. LP Sun, ZQ Lin, J Peng, J weng, YZ Huang, ZQ Luo. Preparation of few-layer bismuth selenide by liquid-phase-exfoliation and its optical absorption properties. Scientific Reports. 2014.4: 4794.

16. J Jia, LP Sun, N Hu, GM Huang, J Weng. Graphene enhances the specificity of the polymerase chain reaction. Small. 2012. 8(13):2011-2015.

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